Throughout the weekend, I spent a lot of time researching canine bone cancer and the various treatment options. This weekend made me appreciate the value the Internet provides. Ten years ago, information would have be a lot less assessable. I found a ton of awesome sites and Yahoo! groups. You can find the links on Newton's "Links" page.
We caught Newton's cancer very early. According to Dr. Ehrhart, it is a Stage II. Stage II means that the cancer has not spread, but can be seen coming through the bone cortex. Based on the X-Rays, that he is giant breed, and the location of the tumor, it sounds like it is most likely Osteosarcoma. Although unlikely, I am told that there is a possibility of other kinds of bone cancer (Fibrosarcoma, Hemangiosarcoma, etc.). Dr. Ehrhart said treatment is very similar for the other tumor types. Armed with this information, I decided that we would pursue the "gold standard" of treatment: Amputation followed by Chemotherapy.
After much discussion, Mary and I decided that the "Gene Therapy for Canine Osteosarcoma" clinical trial would be the one that I would pursue.
I have pet insurance with a cancer rider on Newton. So cost was not really a factor in my decision to pursue a clinical trial. Since the cause of cancer in dogs is largely unknown, I feel that it is important (given the opportunity) to contribute to finding the cause and more effective treatment.